Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | VDR | P11473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938234 | 0.86 | VDR (0.54) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL9542378 | 0.83 | VDR (0.54) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL4897321 | 0.79 | FFAR1 (0.43) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL30901850 | 0.79 | LMNA (0.54) | MEN1KMT2AGAAESR1ESR2 | |
| Propionaldehyde SCHEMBL28280001 | 0.77 | LMNA (0.49) | MEN1KMT2AGAAESR1ESR2 | |
| Iodide SCHEMBL7892639 | 0.77 | ITGB1 (0.44) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL6937775 | 0.76 | KMT2A (0.72) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL5860749 | 0.76 | HSD11B1 (0.53) | MEN1KMT2AGAAESR1ESR2 | |
| Iodide SCHEMBL7892658 | 0.76 | TSHR (0.45) | MEN1KMT2AGAAESR1ESR2 | |
| SCHEMBL2058545 | 0.74 | ALDH1A1 (0.56) | MEN1KMT2AMAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187859-A1 | Radiation-Sensitive Resin Composition | JSR CORPORATION (JP) | 2008-08-07 | — | — | US | disclosed |