Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 8/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970944 | 0.81 | CYP1A2 (0.67) | TDP2CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL4971962 | 0.79 | CYP1A2 (0.56) | TDP2CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL1479810 | 0.78 | TDP2 (0.68) | TDP2KIF11HRH3ASIC3PARP10 | |
| SCHEMBL4759930 | 0.78 | FFAR1 (0.53) | — | |
| SCHEMBL27042635 | 0.78 | TDP2 (0.62) | TDP2KIF11HRH3ASIC3PARP10 | |
| SCHEMBL4889104 | 0.76 | TDP2 (0.47) | TDP2KIF11HRH3ASIC3CHRNB2 | |
| SCHEMBL4889102 | 0.76 | TDP2 (0.47) | TDP2KIF11HRH3ASIC3CHRNB2 | |
| SCHEMBL4971011 | 0.75 | CYP11B1 (0.70) | TDP2CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL4972557 | 0.75 | CYP1A2 (0.52) | KIF11CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL24126858 | 0.75 | CYP11B1 (0.56) | TDP2KIF11CYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | claimed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | TDP2 1033/4885KIF11 562/4885CYP11B1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.