Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | TDP2 | O95551 | 5/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806355 | 0.93 | CYP2A6 (0.59) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL5161609 | 0.86 | CYP1A2 (0.56) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL4971962 | 0.84 | CYP1A2 (0.56) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL27843779 | 0.83 | CYP11B1 (0.49) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL27843802 | 0.83 | CYP11B1 (0.49) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL6253369 | 0.82 | HSD17B3 (0.51) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL4893296 | 0.81 | TDP2 (0.57) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL4888955 | 0.80 | HSD17B3 (0.50) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL4971011 | 0.80 | CYP11B1 (0.70) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL4972557 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101768086-A | Amino methanol derivant and salt compound thereof as well as synthesizing method and medical application thereof | BEIJING FUKA BIOTECHNOLOGY CO | 2010-07-07 | — | — | CN | disclosed |
| WO-2008118790-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-02 | — | — | WO | disclosed |
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC40A1, HAMP | CYP1A2 78/4885CYP11B1 12/4885CYP11B2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.