Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.68 |
| ▸ | KIF11 | P52732 | 10/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1482504 | 0.91 | TDP2 (0.59) | TDP2KIF11ESR1ESR2HRH3 | |
| SCHEMBL33527314 | 0.85 | TDP2 (0.59) | TDP2KIF11ESR1ESR2PARP10 | |
| SCHEMBL13358883 | 0.83 | KIF11 (0.52) | TDP2KIF11ESR1ESR2AGXT | |
| SCHEMBL5684062 | 0.83 | TDP2 (0.51) | TDP2KIF11ESR1ESR2HRH3 | |
| SCHEMBL1482395 | 0.83 | TDP2 (0.51) | TDP2KIF11ESR1ESR2HRH3 | |
| SCHEMBL18010842 | 0.82 | TDP2 (1.00) | TDP2KIF11 | |
| SCHEMBL1904799 | 0.82 | KIF11 (0.50) | TDP2KIF11ESR1ESR2 | |
| SCHEMBL1482704 | 0.78 | CYP3A4 (0.51) | TDP2ESR1ESR2HRH3 | |
| SCHEMBL4893296 | 0.78 | TDP2 (0.57) | TDP2KIF11HRH3CHRNB2CHRNA4 | |
| SCHEMBL197238 | 0.76 | KIF11 (0.78) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293856-B2 | Process for preparing olefin polymer using mixed catalyst | MITSUI CHEMICALS, INC. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20110077369-A1 | PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST | MITSU CHEMICALS, INC. | 2011-03-31 | — | — | US | disclosed |