Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489102 | 0.90 | CYSLTR2 (0.34) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL1332960 | 0.76 | CYSLTR2 (0.45) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL490156 | 0.74 | ALDH1A1 (0.40) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL9857565 | 0.73 | CYSLTR2 (0.40) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL6882280 | 0.73 | CYSLTR2 (0.43) | PPARGCYSLTR2CYSLTR1 | |
| SCHEMBL489694 | 0.72 | LMNA (0.47) | — | |
| SCHEMBL15266613 | 0.72 | PPARG (0.47) | PPARGCYSLTR2CYSLTR1PPARAPSEN1 | |
| SCHEMBL1856281 | 0.71 | CYSLTR2 (0.38) | PPARGCYSLTR2CYSLTR1PRSS1PRSS2 | |
| SCHEMBL1880780 | 0.71 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL8082979 | 0.71 | PPARG (0.45) | PPARGCYSLTR2CYSLTR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106062-B1 | Calcium channel blockers | DIAKRON PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |