SCHEMBL4893707

SCHEMBL4893707

CC(CCCO[Si](C)(C)C(C)(C)C)n1cnc2ncccc21

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.42
DUT P33316 1/20 0.34
LTA4H P09960 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897940 0.81 DUT (0.34) DUT
SCHEMBL22606405 0.77 HIF1A (0.43) HIF1A
SCHEMBL20664871 0.72 HIF1A (0.44) HIF1ALTA4H
SCHEMBL1106477 0.69 HIF1A (0.45) HIF1ALTA4H
SCHEMBL6577204 0.67 CYP2C19 (0.39) HIF1ADUT
SCHEMBL23760241 0.66 HIF1A (0.43) HIF1ALTA4H
SCHEMBL21311454 0.64 HIF1A (0.36) HIF1ALTA4H
SCHEMBL7196866 0.64 HIF1A (0.37) HIF1ALTA4H
SCHEMBL21591572 0.63 HIF1A (0.39) HIF1ALTA4H
SCHEMBL4863671 0.63 HIF1A (0.36) HIF1ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080318878-A1 Antibacterial Agents RANBAXY LABORATRIES LIMITED (IN) 2008-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080318878-A1 Antibacterial Agents MLX, MGAM, CAT HIF1A 919/4885DUT 3176/4885LTA4H 2374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.