SCHEMBL4893738

SCHEMBL4893738

O=C(O)C(O)(Cc1cccnc1)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDPS P14324 8/20 1.00
BTN3A1 O00481 1/20 0.68
PDE3A Q14432 1/20 0.68
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 1/20 0.53
HIF1A Q16665 1/20 0.53
NAPRT Q6XQN6 1/20 0.50
KCNA5 P22460 1/20 0.45
TBXAS1 P24557 4/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Risedronic Acid SCHEMBL18378 0.81 FDPS (1.00) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL29362587 0.81 FDPS (1.00) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL4989214 0.80 FDPS (0.97) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL3170751 0.80 FDPS (0.97) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL3771017 0.80 FDPS (0.97) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL2115054 0.80 FDPS (0.97) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL2115050 0.80 FDPS (0.97) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL2324758 0.78 FDPS (0.81) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL2324063 0.78 FDPS (0.81) FDPSBTN3A1PDE3ACYP1A2CYP3A4
Risedronic Acid SCHEMBL22720090 0.78 FDPS (0.94) FDPSBTN3A1PDE3ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683668-A1 COMPOSITIONS AND METHODS FOR TREATING TENDON AND BONE INJURIES The United States Government as Represented by The Department of Veterans Affairs (US) 2026-01-28 EP claimed
WO-2024233344-A1 COMPOSITIONS AND METHODS FOR TREATING TENDON AND BONE INJURIES THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2024-11-14 WO claimed
CN-118121702-A Specific inhibitor of targeted GGTase II and application thereof 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 2024-06-04 CN claimed
CN-115808525-A Application of RabGGTase in diagnosis and treatment of amyotrophic lateral sclerosis 河北医科大学第二医院 2023-03-17 CN claimed
US-11400104-B2 Skeletal removal of bisphosphonates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-02 US claimed
CN-109219438-B Bone removal of bisphosphonates 加州大学董事会 2022-04-22 CN claimed
US-20210121485-A1 Skeletal Removal of Bisphosphonates UNIV CALIFORNIA (US) 2021-04-29 US claimed
EP-4683668-A1 COMPOSITIONS AND METHODS FOR TREATING TENDON AND BONE INJURIES The United States Government as Represented by The Department of Veterans Affairs (US) 2026-01-28 EP disclosed
WO-2024233344-A1 COMPOSITIONS AND METHODS FOR TREATING TENDON AND BONE INJURIES THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2024-11-14 WO disclosed
CN-118453584-A Application of lipophilic statin in preparation of medicines for treating autoimmune diseases related to antibody secreting cells 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 2024-08-09 CN disclosed
CN-118121702-A Specific inhibitor of targeted GGTase II and application thereof 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 2024-06-04 CN disclosed
CN-115808525-A Application of RabGGTase in diagnosis and treatment of amyotrophic lateral sclerosis 河北医科大学第二医院 2023-03-17 CN disclosed
CN-115808525-A Application of RabGGTase in diagnosis and treatment of amyotrophic lateral sclerosis 河北医科大学第二医院 2023-03-17 CN disclosed
EP-0788362-B1 PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM PROCTER & GAMBLE PHARMA (US) 2001-07-25 EP disclosed
CN-1048017-C Phosphonocarboxylate compounds and pharmaceutical compositions containing the same PROCTER & GAMBLE PHARMA (US) 2000-01-05 CN disclosed
CN-1224018-A Phosphonic carboxylate compounds, pharmaceutical compositions contg. same PROCTER & GAMBLE PHARMA (US) 1999-07-28 CN disclosed
US-5760021-A TREATING OR PREVENTING METABOLIC BONE DISORDERS THE PROCTER & GAMBLE COMPANY (US) 1998-06-02 US disclosed
EP-0788362-A1 PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1997-08-13 EP disclosed
CN-1089613-A Phosphonocarboxylate compounds and pharmaceutical compositions containing the same PROCTER & GAMBLE PHARMA (US) 1994-07-20 CN disclosed
WO-1993024131-A1 PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1993-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210121485-A1 Skeletal Removal of Bisphosphonates SOST, ACP3, PTH1R FDPS 1272/4885BTN3A1 2262/4885PDE3A 1115/4885
US-11400104-B2 Skeletal removal of bisphosphonates SOST, ACP3, PTH1R FDPS 1272/4885BTN3A1 2262/4885PDE3A 1115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.