Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27464056 | 0.92 | ALOX15 (0.43) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| Propylamine SCHEMBL27713757 | 0.90 | LMNA (0.42) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| Butane SCHEMBL27617980 | 0.90 | LMNA (0.45) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| Alcohol SCHEMBL6545350 | 0.90 | ALOX15 (0.42) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| Ethylenediamine SCHEMBL5093336 | 0.90 | ALOX15 (0.36) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| SCHEMBL28902273 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| SCHEMBL28325001 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| SCHEMBL3094 | 0.89 | — | — | |
| SCHEMBL30234788 | 0.89 | DGAT1 (0.42) | ALOX15LMNAHSD17B10DGAT1MAOA | |
| Ethyl Chloride SCHEMBL28678554 | 0.87 | ALOX15 (0.40) | ALOX15LMNAHSD17B10DGAT1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608863-A | Preparation method of landiolol hydrochloride | 北京创立科创医药技术开发有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-103002921-A | Functionally crosslinked nanostructures for combined optical imaging and therapy | MALLINCKRODT LLC | 2013-03-27 | — | — | CN | disclosed |
| US-7273904-B2 | Nanocrystals in ligand boxes exhibiting enhanced chemical, photochemical, and thermal stability, and methods of making the same | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2007-09-25 | — | — | US | disclosed |
| US-20050004293-A1 | Nanocrystals in ligand boxes exhibiting enhanced chemical, photochemical, and thermal stability, and methods of making the same | NAJING TECHNOLOGY CORPORATION LIMITED (CN) | 2005-01-06 | — | — | US | disclosed |
| US-6831175-B2 | Such as N,N-dimethyl-N-(2-((5-((E)-2-pyridin-4-ylvinyl) pyridin-3-yl)oxy)ethyl)amine | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| EP-1463505-A2 | 3-(PHENYL-ALKOXY)-5-(PHENYL)-PYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Abbott Laboratories (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2004031732-A2 | NANOCRYSTALS IN LIGAND BOXES EXHIBITING ENHANCED CHEMICAL, PHOTOCHEMICAL, AND THERMAL STABILITY, AND METHODS OF MAKING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2004-04-15 | — | — | WO | disclosed |
| US-20030199511-A1 | Kinase inhibitors | ABBVIE INC. | 2003-10-23 | — | — | US | disclosed |
| US-20030187026-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-02 | — | — | US | disclosed |
| WO-2003051366-A2 | 3-(PHENYL-ALKOXY)-5-(PHENYL)-PYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ABBOTT LABORATORIES (US) | 2003-06-26 | — | — | WO | disclosed |
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187026-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | ALOX15 4082/4885LMNA 3109/4885HSD17B10 2153/4885 |
| US-20030199511-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | ALOX15 4082/4885LMNA 3109/4885HSD17B10 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.