SCHEMBL4894473

SCHEMBL4894473

CS(=O)(=O)ON=C(c1ccccc1)C(F)(F)[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.36
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
KMT2A Q03164 4/20 0.32
MEN1 O00255 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PTGS2 P35354 2/20 0.31
CES1 P23141 3/20 0.31
FAAH O00519 2/20 0.31
MGLL Q99685 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
CES2 O00748 2/20 0.30
ACHE P22303 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4895434 0.86 ALDH1A1 (0.35) ESR2ALDH1A1HTTMCOLN3KMT2A
SCHEMBL546379 0.82 CES1 (0.40) ALDH1A1HTTKMT2AMEN1LMNA
SCHEMBL546378 0.82 CES1 (0.40) ALDH1A1HTTKMT2AMEN1LMNA
SCHEMBL4895556 0.81 GAA (0.37) ALDH1A1HTTKMT2AMEN1LMNA
SCHEMBL4903514 0.78 PTGS2 (0.34) KMT2APTGS2CES1PPARGPPARA
SCHEMBL4897399 0.77 CES1 (0.36) ALDH1A1HTTKMT2ALMNAMAPT
SCHEMBL5442975 0.77 KMT2A (0.35) ALDH1A1KMT2AMEN1MAPTCES1
SCHEMBL4891641 0.77 KMT2A (0.35) ALDH1A1MCOLN3KMT2AMEN1LMNA
SCHEMBL4903574 0.76 CES1 (0.32) MAPTNPSR1CES1
SCHEMBL4902187 0.75 SRC (0.42) ALDH1A1HTTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed