Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816081 | 0.76 | CYP3A4 (0.39) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL2226790 | 0.76 | CYP3A4 (0.39) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| Hydrochloric Acid SCHEMBL16431629 | 0.74 | TDP1 (0.38) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL14088328 | 0.73 | CYP3A4 (0.36) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL8666391 | 0.70 | CHRM2 (0.32) | CYP3A4TDP1L3MBTL1CHRM2HTR1A | |
| SCHEMBL9566535 | 0.68 | L3MBTL1 (0.35) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL18806837 | 0.68 | LMNA (0.33) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL9864179 | 0.67 | CYP3A4 (0.39) | CYP3A4TDP1L3MBTL1TSHRTP53 | |
| SCHEMBL22882933 | 0.66 | KDM4E (0.38) | CYP3A4TDP1L3MBTL1ALDH1A1AOC3 | |
| SCHEMBL9619532 | 0.65 | SIGMAR1 (0.44) | CYP3A4TSHRALDH1A1CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |