SCHEMBL2226790

SCHEMBL2226790

CCN(CC)P(c1ccccc1)N(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
GLA P06280 1/20 0.35
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRM1 P35372 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26434909 0.83 PGR (0.33) CYP3A4TDP1L3MBTL1LMNAADRA2A
SCHEMBL11506410 0.81 TP53 (0.36) CYP3A4TDP1TP53HTR1ASLC6A2
SCHEMBL4816081 0.80 CYP3A4 (0.39) CYP3A4TDP1L3MBTL1LMNATP53
SCHEMBL17828677 0.79 PGR (0.31) ADRA2AKCNH2
Hydrochloric Acid SCHEMBL16431629 0.78 TDP1 (0.38) CYP3A4TDP1L3MBTL1LMNATP53
SCHEMBL11571279 0.78 TDP1 (0.43) TDP1CHRM2HTR1AADRA2ACHRM1
SCHEMBL4894932 0.76 CYP3A4 (0.36) CYP3A4TDP1L3MBTL1LMNATP53
SCHEMBL14088328 0.76 CYP3A4 (0.36) CYP3A4TDP1L3MBTL1LMNATP53
SCHEMBL22015893 0.75 TDP1 (0.35) CYP3A4TDP1TP53TSHRALDH1A1
SCHEMBL22022223 0.73 KCNH2 (0.41) TDP1OPRM1DRD3KCNH2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008127-B Ethylene-based polymer compositions containing triorganoaminophosphines 陶氏环球技术有限责任公司 2024-01-19 CN claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
CN-122029245-A Use of a composition for improving adhesive bonding of surfaces and method for bonding surfaces 法国特种经营公司 2026-05-12 CN disclosed
US-20260103443-A1 CHEMICAL COMPOUND LMS CO LTD (KR) 2026-04-16 US disclosed
EP-4695220-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS SPECIALTY OPERATIONS FRANCE (FR) 2026-02-18 EP disclosed
EP-4695222-A1 PROCESS FOR PREPARING ESTERAMIDE COMPOUNDS SPECIALTY OPERATIONS FRANCE (FR) 2026-02-18 EP disclosed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 US disclosed
US-20250230119-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS SPECIALTY OPERATIONS FRANCE (FR) 2025-07-17 US disclosed
US-20250197346-A1 COMPOUND FOR OPTICAL ABSORBENT LMS CO., LTD. (KR) 2025-06-19 US disclosed
CN-120157599-A Compounds for light absorbers 株式会社LMS 2025-06-17 CN disclosed
US-5767276-A Asymmetric synthesis catalyzed by transition metal complexes with new chiral ligands THE PENN STATE RESEARCH FOUNDATION (US) 1998-06-16 US disclosed
WO-1997013763-A1 ASYMMETRIC SYNTHESIS CATALYZED BY TRANSITION METAL COMPLEXES WITH NEW CHIRAL LIGANDS THE PENN STATE RESEARCH FOUNDATION (US) 1997-04-17 WO disclosed
US-5068425-A Nervous system disorders, intermediates for drugs and as enantiomorphs SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-11-26 US disclosed
US-4983768-A Reacting an organic halide and an oxazaphospholidine in the absence of air, humidity and light SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-01-08 US disclosed
EP-0082057-B1 PROCESS FOR PREPARING PHOSPHINAMIDES, APPLICATIONS AND PRODUCTS SOCIETE NATIONALE ELF AQUITAINE (FR) 1986-04-30 EP disclosed
EP-0082057-A2 Process for preparing phosphinamides, applications and products SOCIETE NATIONALE ELF AQUITAINE (FR) 1983-06-22 EP disclosed
US-4263231-A REACTING DICHLOROPHOSPHANES AND 2-N-ACYLAMINOPHENOLS HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-21 US disclosed
US-4155946-A CATALYST CONSISTS OF A NICKEL COMPOUND, A TRIALKYL ALUMINUM COMPOUND; PHOSPHOROUS COMPOUND AND A HALOGENATED PHENOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 CYP3A4 841/4885TDP1 3585/4885L3MBTL1 4245/4885
US-20250197346-A1 COMPOUND FOR OPTICAL ABSORBENT CDH1, SUN2, HSF1 CYP3A4 2405/4885TDP1 4614/4885L3MBTL1 2937/4885
US-20260103443-A1 CHEMICAL COMPOUND RAD51, CBR1, NOS1 CYP3A4 222/4885TDP1 4386/4885L3MBTL1 3648/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP CYP3A4 4442/4885TDP1 3996/4885L3MBTL1 4615/4885
US-20250230119-A1 PROCESSES FOR PRODUCING ALKYL ACRYLATE DIMERS HDHD5, ABHD5, HACL2 CYP3A4 697/4885TDP1 1213/4885L3MBTL1 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.