Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811424 | 0.83 | MEN1 (0.49) | MEN1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL6815125 | 0.83 | MEN1 (0.58) | MEN1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL6810635 | 0.77 | RAB9A (0.53) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL28429878 | 0.77 | MEN1 (0.60) | MEN1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL2461958 | 0.77 | MEN1 (0.65) | MEN1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL6816886 | 0.76 | MEN1 (0.53) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11260248 | 0.76 | HTR3E (0.43) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL30503043 | 0.75 | MAPT (0.74) | MEN1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL653293 | 0.75 | HTR3E (0.50) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL5353973 | 0.74 | MEN1 (0.56) | MEN1KMT2AMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
| US-5443909-A | Heat sensitive recordin material; substrate, recording layer containing colorless basic dye and protective coatings | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5439869-A | Substrate coated with a mixture of a bisphenol carboxylic acid, one basic compound, and a color developer; colorfastness, storage stability, chemical resistance | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| US-5292712-A | Salt of a bisphenol carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027044-A1 | Prodrug antibiotic screens | O60361, PGLS, GUSB | MEN1 3696/4885KMT2A 3307/4885HSP90AA1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.