SCHEMBL4896677

SCHEMBL4896677

C=CCc1ccc(S(=O)(=O)O)c(CC=C)c1CC=C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
TDP1 Q9NUW8 1/20 0.33
SRD5A1 P18405 3/20 0.32
ELANE P08246 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5183081 0.89 POLB (0.39) POLBGABRA1GABRB2TDP1SRD5A1
SCHEMBL367941 0.86 GABRA1 (0.44) POLBGABRA1GABRB2ELANE
SCHEMBL7107164 0.84 GABRA1 (0.43) POLBGABRA1GABRB2ELANE
Magnesium SCHEMBL2052962 0.84 GABRA1 (0.43) POLBGABRA1GABRB2ELANE
SCHEMBL2059595 0.80 POLB (0.33) POLB
SCHEMBL11764994 0.80 POLB (0.40) POLBGABRA1GABRB2
SCHEMBL1918099 0.79 GABRA1 (0.43) POLBGABRA1GABRB2SRD5A1
Trolamine SCHEMBL28619894 0.79 GABRA1 (0.36) POLBGABRA1GABRB2
SCHEMBL27660929 0.79 POLB (0.39) POLBGABRA1GABRB2TDP1ELANE
Sulfuric Acid SCHEMBL3191044 0.79 IMPDH2 (0.40) POLBGABRA1GABRB2SRD5A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11920103-B2 Mineral-oil-free lubricant and method for producing a mineral-oil-free lubricant Kajo GmbH (DE) 2024-03-05 US claimed
CN-113366096-B Mineral oil-free lubricant and method of making a mineral oil-free lubricant 卡乔有限责任公司 2023-03-17 CN claimed
US-20220056365-A1 Mineral-Oil-Free Lubricant And Method For Producing A Mineral-Oil-Free Lubricant Kajo GmbH (DE) 2022-02-24 US claimed
CN-113366096-A Mineral oil-free lubricant and method of making a mineral oil-free lubricant 卡乔有限责任公司 2021-09-07 CN claimed
US-5368776-A Corrosion protection additives based on epoxides RHEIN CHEMIE RHEINAU GMBH (DE) 1994-11-29 US claimed
US-11920103-B2 Mineral-oil-free lubricant and method for producing a mineral-oil-free lubricant Kajo GmbH (DE) 2024-03-05 US disclosed
CN-113366096-B Mineral oil-free lubricant and method of making a mineral oil-free lubricant 卡乔有限责任公司 2023-03-17 CN disclosed
US-20220056365-A1 Mineral-Oil-Free Lubricant And Method For Producing A Mineral-Oil-Free Lubricant Kajo GmbH (DE) 2022-02-24 US disclosed
CN-113366096-A Mineral oil-free lubricant and method of making a mineral oil-free lubricant 卡乔有限责任公司 2021-09-07 CN disclosed
US-7365066-B2 Pyrazolopyridine derivatives as pharmaceutical agents ELI LILLY AND COMPANY (US) 2008-04-29 US disclosed
EP-1543001-B1 PYRAZOLOPYRIDINE DERIVATIVES AS TGF BETA SIGNAL TRANSDUCTION INHIBITORS FOR THE TREATMENT OF CANCER LILLY CO ELI (US) 2007-08-15 EP disclosed
US-20050222197-A1 Novel pyrazolopyridine derivatives as pharmaceutical agents BEIGHT DOUGLAS W 2005-10-06 US disclosed
EP-1543001-A1 NOVEL PYRAZOLOPYRIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS ELI LILLY AND COMPANY (US) 2005-06-22 EP disclosed
WO-2004026871-A1 NOVEL PYRAZOLOPYRIDINE DERIVATVES AS PHARMACEUTICAL AGENTS ELI LILLY AND COMPANY (US) 2004-04-01 WO disclosed
US-4842067-A USING MIXTURE OF SULFONATED SURFACTANTS HUELS AKTIENGESELLSCHAFT (DE) 1989-06-27 US disclosed
US-4705110-A SALTS OF CARBOXYMETHYLATED OXYETHYLATES HUELS AKTIENGESELLSCHAFT (DE) 1987-11-10 US disclosed
US-3957425-A DISAZO DYES, SOLVENT DYES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222197-A1 Novel pyrazolopyridine derivatives as pharmaceutical agents TGFB2, TGFB1, TGFBR1 POLB 1643/4885GABRA1 3056/4885GABRB2 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.