Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313299 | 0.77 | LMNA (0.45) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL17221547 | 0.77 | NOS1 (0.45) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL11301720 | 0.73 | NOS1 (0.50) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL10732234 | 0.71 | CYP1A2 (0.52) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL13681634 | 0.71 | NOS1 (0.52) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL8253228 | 0.68 | NOS1 (0.49) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL17261393 | 0.68 | NOS1 (0.49) | SIRT2CYP1A2LMNAADRA2ATSHR | |
| SCHEMBL31139539 | 0.68 | NOS1 (0.49) | CYP1A2LMNAADRA2ATSHRNOS3 | |
| SCHEMBL13688720 | 0.67 | NOS1 (0.47) | TSHRNOS3NOS1NOS2KMO | |
| SCHEMBL3625570 | 0.67 | ALOX5 (0.44) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | PURDUE RESEARCH FOUNDATION (US) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | POLRMT, PNP, TYMS | SIRT2 2248/4885HCAR2 4030/4885CYP1A2 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.