Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893886 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPTNPSR1POLB | |
| SCHEMBL4902565 | 0.77 | TET2 (0.41) | NPSR1TET2SMN1; SMN2POLB | |
| SCHEMBL4906424 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPT | |
| SCHEMBL14086409 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPTNPSR1ATM | |
| Phosphoric Acid SCHEMBL10696160 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL12130916 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTNPSR1TET2 | |
| SCHEMBL17687582 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTNPSR1TET2 | |
| SCHEMBL7920777 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTNPSR1EGLN1 | |
| SCHEMBL28646152 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTNPSR1TET2 | |
| SCHEMBL16830099 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | GRHPR, PHPT1, PHYKPL | ALDH1A1 493/4885TSHR 3136/4885MAPT 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.