Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911943 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPTPPARD | |
| SCHEMBL4893886 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPT | |
| SCHEMBL7920777 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTPPARD | |
| SCHEMBL10468127 | 0.80 | MAPT (0.37) | ALDH1A1TSHRMAPTPPARD | |
| SCHEMBL7919064 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPT | |
| SCHEMBL4896828 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPT | |
| SCHEMBL4903214 | 0.76 | MAPK1 (0.32) | MAPT | |
| SCHEMBL11749488 | 0.76 | MAPT (0.32) | MAPT | |
| SCHEMBL22490102 | 0.75 | TET2 (0.41) | ALDH1A1TSHRMAPT | |
| SCHEMBL2770601 | 0.74 | MEN1 (0.43) | ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200679-A1 | Alpha-HYDROXY, alpha-SUBSTITUTED METHYLENEBISPHOSPHONATES AND PHOSPHONOACETATES | GRHPR, PHPT1, PHYKPL | ALDH1A1 493/4885TSHR 3136/4885MAPT 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.