Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894795 | 0.98 | ACE2 (0.52) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL4894258 | 0.98 | ACE2 (0.52) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL4897448 | 0.98 | ACE2 (0.52) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL4897015 | 0.93 | ACE2 (0.41) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL4898571 | 0.83 | TSHR (0.48) | ACE2MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL27610814 | 0.82 | ACE2 (0.48) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL4904464 | 0.80 | ACE2 (0.58) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL20509650 | 0.79 | ACE2 (0.45) | ACE2OPRM1CA1SPHK1LMNA | |
| SCHEMBL22129693 | 0.77 | ACE2 (0.62) | ACE2OPRM1SPHK1LMNAPRKD3 | |
| SCHEMBL20506755 | 0.77 | ACE2 (0.62) | ACE2OPRM1SPHK1LMNAPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080003277-A1 | Agent for improving tissue penetration | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSHAFTEN E.V. (DE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080003277-A1 | Agent for improving tissue penetration | PGF, MMP8, MMP1 | ACE2 1277/4885OPRM1 1745/4885CA1 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.