Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897015 | 0.85 | ACE2 (0.41) | TSHRMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL4897818 | 0.83 | ACE2 (0.48) | MEN1CYP3A4ALOX15KMT2AACE2 | |
| SCHEMBL4897448 | 0.81 | ACE2 (0.52) | ACE2 | |
| SCHEMBL4894795 | 0.81 | ACE2 (0.52) | ACE2 | |
| SCHEMBL4894258 | 0.81 | ACE2 (0.52) | ACE2 | |
| SCHEMBL4891764 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL56451 | 0.76 | — | — | |
| SCHEMBL18993461 | 0.76 | TSHR (0.43) | TSHR | |
| SCHEMBL10289899 | 0.76 | TSHR (0.43) | TSHR | |
| SCHEMBL15160445 | 0.76 | TSHR (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080003277-A1 | Agent for improving tissue penetration | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSHAFTEN E.V. (DE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080003277-A1 | Agent for improving tissue penetration | PGF, MMP8, MMP1 | TSHR 2132/4885MEN1 2672/4885CYP3A4 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.