Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667488 | 0.88 | HDAC2 (0.55) | ALDH1A1CYP1A2POLBAPEX1TDP1 | |
| SCHEMBL9054973 | 0.85 | RAPGEF4 (0.60) | ALDH1A1CYP1A2SMN1; SMN2HPGDATIC | |
| SCHEMBL4903408 | 0.85 | HSD17B10 (0.55) | ALDH1A1CYP1A2SMN1; SMN2HSD17B10POLB | |
| SCHEMBL11409686 | 0.84 | MAPT (0.56) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL392265 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HPGDMEN1LMNA | |
| SCHEMBL10877294 | 0.81 | MEN1 (0.58) | ALDH1A1CYP1A2SMN1; SMN2HPGDATIC | |
| SCHEMBL27141426 | 0.81 | TIMP3 (0.65) | ALDH1A1CYP1A2SMN1; SMN2HPGDATIC | |
| SCHEMBL10049707 | 0.81 | MEN1 (0.41) | ALDH1A1CYP1A2SMN1; SMN2HPGDATIC | |
| SCHEMBL13425425 | 0.80 | MAPT (0.36) | ALDH1A1CYP1A2SMN1; SMN2HPGDATIC | |
| SCHEMBL4905389 | 0.79 | MEN1 (0.60) | SMN1; SMN2POLBAPEX1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | LENNARTZ MICHAEL | 2008-05-22 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| EP-0774493-B1 | Fiber-reactive azo dyestuffs, process for their preparation and use thereof | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2001-04-04 | — | — | EP | disclosed |
| EP-0735113-B1 | Mixtures of reactive dyes and their use | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0627471-B1 | Reactive dyes | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| EP-0652262-B1 | Reactive dyestuffs, their preparation and use | BAYER AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| EP-0114032-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | disclosed |
| US-4447357-A | Fibre-reactive azo dyestuffs containing a halotriazinyl radical and a non-reactive triazinyl radical | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0097119-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| EP-0096659-A2 | Process for dyeing or printing fibrous textile materials with reactive dyes | CIBA-GEIGY AG (CH) | 1983-12-21 | — | — | EP | disclosed |
| EP-0089923-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1983-09-28 | — | — | EP | disclosed |
| US-4330469-A | Reactive dyes, processes for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0036838-A2 | Azo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| US-4270918-A | METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE | CIBA-GEIGY CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |
| US-4228071-A | Triazine containing fiber-reactive disazo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4066389-A | SULFOPHENYLAMINO CONTAINING TETRAREACTIVE TRIAZINE DISAZO DYESTUFFS AND DYESTUFF COMPOSITIONS THEREOF | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | CYP4B1, TYR, DDT | ALDH1A1 155/4885CYP1A2 21/4885SMN1; SMN2 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.