Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CD40 | P25942 | 2/20 | 0.53 |
| ▸ | CD40LG | P29965 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411204 | 0.87 | RAB9A (0.56) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4898797 | 0.84 | ALDH1A1 (0.47) | MAPTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11736141 | 0.84 | MEN1 (0.61) | MAPTRAB9ACD40CD40LGNT5E | |
| SCHEMBL11706405 | 0.82 | MAPT (0.54) | MAPTRAB9ANPC1HTTALDH1A1 | |
| SCHEMBL8667488 | 0.81 | HDAC2 (0.55) | MAPTALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL10887712 | 0.81 | CD40 (0.56) | MAPTRAB9ACD40CD40LGNT5E | |
| SCHEMBL11797457 | 0.79 | NPC1 (0.66) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL11597131 | 0.79 | HCAR3 (0.56) | MAPTRAB9ACD40CD40LGNPC1 | |
| SCHEMBL11431489 | 0.79 | MAPT (0.52) | MAPTRAB9ACD40CD40LGNT5E | |
| SCHEMBL11346516 | 0.78 | HDAC2 (0.64) | MAPTRAB9ANPC1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228071-A | Triazine containing fiber-reactive disazo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |