Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 11/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898797 | 0.88 | ALDH1A1 (0.47) | HDAC2HDAC1HDAC3MAPK1MEN1 | |
| SCHEMBL4903408 | 0.87 | HSD17B10 (0.55) | HDAC2HDAC1HDAC3MAPK1MEN1 | |
| SCHEMBL11597131 | 0.83 | HCAR3 (0.56) | HDAC2HDAC1HDAC3MAPK1MEN1 | |
| SCHEMBL9353760 | 0.82 | MAPT (0.62) | HDAC2HDAC1HDAC3MAPK1MEN1 | |
| SCHEMBL11409686 | 0.81 | MAPT (0.56) | HDAC2HDAC1MEN1KMT2AMAPT | |
| SCHEMBL11411204 | 0.81 | RAB9A (0.56) | HDAC2HDAC1HDAC3MEN1KMT2A | |
| SCHEMBL11596615 | 0.80 | HCAR3 (0.56) | HDAC2HDAC1HDAC3MAPK1POLB | |
| SCHEMBL8673667 | 0.79 | KCNK3 (0.54) | MEN1KMT2AMAPTPKM | |
| SCHEMBL7555076 | 0.79 | KCNK3 (0.54) | MEN1KMT2AMAPTPKM | |
| SCHEMBL2893166 | 0.78 | MDM4 (0.56) | HDAC2HDAC1HDAC3MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786476-A | UV absorbers, their preparation and use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| EP-0218131-B1 | WATER SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |
| US-4902786-A | Phenylazonaphthol or naphthylazonaphthol compounds containing a fibre-reactive aminophenylamino-substituted halogen-s-triazinylamino group and a fibre-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-20 | — | — | US | disclosed |
| US-4775746-A | Water-soluble monoazo compounds containing a fiber-reactive group of the vinylsulfone series and having a sulfonaphthol coupling component with a phenylaminotriazinylamino substituent, suitable as dyestuffs | HOECHST AKTIENGESELLSHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| US-4757136-A | Water-soluble Azo compounds containing fiber-reactive groups and having a sulfo-naphthol coupling component with a triazinylamino substituent suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4740592-A | Water-soluble azo compounds containing fiber-reactive groups and having a sulfo-naphthal coupling component with a triazinylamino substituent suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |