Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123636 | 0.83 | NQO1 (0.40) | ALDH1A1NPC1MAPTRAB9AHSP90AA1 | |
| SCHEMBL51038 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL11987589 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL13945607 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL697079 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL18894874 | 0.80 | TSHR (0.51) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL17485950 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1TSHRNPC1MAPTRAB9A | |
| SCHEMBL25005379 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL11987592 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4ENPC1MAPT | |
| SCHEMBL11987590 | 0.78 | HCAR2 (0.51) | ALDH1A1TSHRKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164465-A | Phenyl cyclopropylamine compound and preparation method and application thereof | 郑州大学 | 2023-12-05 | — | — | CN | disclosed |
| US-20080221205-A1 | FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | OSCOTEC INC. (KR) | 2008-09-11 | — | — | US | disclosed |
| US-20060004088-A1 | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same | OCT INC. (KR) | 2006-01-05 | — | — | US | disclosed |
| WO-2004037804-A1 | FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | OSCOTEC INC. (KR) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004088-A1 | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same | SOST, PTH1R, PTMS | ALDH1A1 784/4885TSHR 4252/4885KDM4E 301/4885 |
| US-20080221205-A1 | FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SOST, PTH1R, PTMS | ALDH1A1 784/4885TSHR 4252/4885KDM4E 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.