SCHEMBL697079

SCHEMBL697079

CCC(=O)OCc1ccc(C=O)o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
TSHR P16473 1/20 0.51
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
KDM4E B2RXH2 4/20 0.43
MAPT P10636 3/20 0.43
HSP90AA1 P07900 1/20 0.43
HPGD P15428 3/20 0.43
POLB P06746 3/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
STAT1 P42224 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.40
HTT P42858 1/20 0.40
LDHA P00338 1/20 0.36
LDHB P07195 1/20 0.36
HAO1 Q9UJM8 1/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 3/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14060191 0.90 SMN1; SMN2 (0.44) ALDH1A1TSHRNPC1RAB9AKDM4E
SCHEMBL14118840 0.88 ALDH1A1 (0.49) ALDH1A1TSHRNPC1RAB9AKDM4E
SCHEMBL51038 0.83 ALDH1A1 (0.55) ALDH1A1TSHRNPC1RAB9AKDM4E
SCHEMBL18740423 0.83 ALDH1A1 (0.47) ALDH1A1TSHRNPC1RAB9AKDM4E
SCHEMBL19226105 0.83 ELANE (0.50) ALDH1A1TSHR
SCHEMBL18640566 0.83 ELANE (0.50) ALDH1A1TSHR
SCHEMBL18640548 0.83 ELANE (0.50) ALDH1A1TSHR
SCHEMBL19226024 0.83 ELANE (0.50) ALDH1A1TSHR
SCHEMBL21854812 0.83 ELANE (0.50) ALDH1A1TSHR
SCHEMBL19226025 0.83 ELANE (0.50) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112830916-B Preparation method of 2, 5-furandicarboxylic acid under mild condition 中国科学院宁波材料技术与工程研究所 2021-08-13 CN claimed
CN-112830916-A Preparation method of 2, 5-furandicarboxylic acid under mild condition 中国科学院宁波材料技术与工程研究所 2021-05-25 CN claimed
EP-3653612-B1 METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE BY PHYSICAL SEPARATION AND SOLID LIQUID SEPARATION EASTMAN CHEM CO (US) 2024-01-17 EP disclosed
EP-3578552-B1 AN OXIDATION PROCESS TO PRODUCE A PURIFIED CARBOXYLIC ACID PRODUCT VIA SOLVENT DISPLACEMENT AND POST OXIDATION EASTMAN CHEM CO (US) 2023-06-07 EP disclosed
US-11655227-B2 Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant EASTMAN CHEMICAL COMPANY (US) 2023-05-23 US disclosed
US-11655227-B2 Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant EASTMAN CHEMICAL COMPANY (US) 2023-05-23 US disclosed
WO-2023014553-A1 INTEGRATED PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) EASTMAN CHEMICAL COMPANY (US) 2023-02-09 WO disclosed
WO-2022245625-A1 PURGE PROCESS FOR 5-(METHOXYCARBONYL)FURAN-2-CARBOXYLIC ACID (MCFC) EASTMAN CHEMICAL COMPANY (US) 2022-11-24 WO disclosed
EP-3321260-B1 COMPOSITION OBTAINED BY PURIFYING CRUDE FURAN 2,5-DICARBOXYLIC ACID BY HYDROGENATION EASTMAN CHEM CO (US) 2022-07-13 EP disclosed
CN-112830916-B Preparation method of 2, 5-furandicarboxylic acid under mild condition 中国科学院宁波材料技术与工程研究所 2021-08-13 CN disclosed
US-11066376-B2 Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant EASTMAN CHEMICAL COMPANY (US) 2021-07-20 US disclosed
WO-2009076627-A2 CONVERSION OF CARBOHYDRATES TO HYDROXY-METHYLFURFURAL (HMF) AND DERIVATIVES ARCHER DANIELS MIDLAND CO (US) 2009-06-18 WO disclosed
WO-2009076627-A2 CONVERSION OF CARBOHYDRATES TO HYDROXY-METHYLFURFURAL (HMF) AND DERIVATIVES ARCHER DANIELS MIDLAND CO (US) 2009-06-18 WO disclosed
US-20090156841-A1 CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES ARCHER DANIELS MIDLAND CO. 2009-06-18 US disclosed
US-20090156841-A1 CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES ARCHER DANIELS MIDLAND CO. 2009-06-18 US disclosed
US-20090156841-A1 CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES ARCHER DANIELS MIDLAND CO. 2009-06-18 US disclosed
CN-101421259-A Synthesis method and application of 5-hydroxymethylfurfural organic acid ester FURANIX TECHNOLOGIES BV (NL) 2009-04-29 CN disclosed
WO-2009030512-A2 HYDROXYMETHYLFURFURAL ETHERS AND ESTERS PREPARED IN IONIC LIQUIDS FURANIX TECHNOLOGIES B.V. (NL) 2009-03-12 WO disclosed
EP-2001859-A1 METHOD FOR THE SYNTHESIS OF ORGANIC ACID ESTERS OF 5-HYDROXYMETHYLFURFURAL AND THEIR USE Furanix Technologies B.V (NL) 2008-12-17 EP disclosed
WO-2007104515-A1 METHOD FOR THE SYNTHESIS OF ORGANIC ACID ESTERS OF 5-HYDROXYMETHYLFURFURAL AND THEIR USE FURANIX TECHNOLOGIES B.V. (NL) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066376-B2 Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant DDC, DLAT, FDFT1 ALDH1A1 127/4885TSHR 3251/4885NPC1 2618/4885
US-20090156841-A1 CONVERSION OF CARBOHYDRATES TO HYDROXYMETHYLFURFURAL (HMF) AND DERIVATIVES HPD, FOS, MCCC2 ALDH1A1 953/4885TSHR 3037/4885NPC1 1602/4885
US-11655227-B2 Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant DDC, DLAT, FDFT1 ALDH1A1 127/4885TSHR 3251/4885NPC1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.