Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029797 | 0.89 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL9619418 | 0.85 | CYP3A4 (0.38) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL10705336 | 0.82 | CYP3A4 (0.45) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL9619306 | 0.81 | LTA4H (0.35) | CYP3A4TDP1TSHRKDM4ECES2 | |
| SCHEMBL15285713 | 0.79 | ALDH1A1 (0.35) | CYP3A4TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15285876 | 0.79 | LTA4H (0.36) | TDP1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL28897741 | 0.79 | ALDH1A1 (0.34) | CYP3A4TDP1TSHRKDM4ELMNA | |
| SCHEMBL2154391 | 0.78 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL8639182 | 0.78 | DNM1 (0.38) | TDP1CES2CES1SMN1; SMN2 | |
| SCHEMBL8070483 | 0.78 | DNM1 (0.38) | TDP1CES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |