Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2154232 | 0.98 | TSHR (0.41) | TSHRLMNACYP2A6ALDH1A1AKR1B1 | |
| SCHEMBL9251163 | 0.84 | TSHR (0.38) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL246944 | 0.84 | TSHR (0.53) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL30603849 | 0.82 | TSHR (0.37) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL8013185 | 0.82 | TSHR (0.36) | TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2155084 | 0.81 | TSHR (0.50) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL288549 | 0.81 | CA1 (0.37) | TSHRLMNAALDH1A1 | |
| SCHEMBL29242283 | 0.76 | LMNA (0.35) | TSHRLMNACYP2A6CYP1A2 | |
| SCHEMBL4061116 | 0.74 | CA12 (0.32) | — | |
| SCHEMBL7777360 | 0.72 | TSHR (0.39) | TSHRLMNAALDH1A1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648549-A | Process for the preparation of secondary arylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | claimed |
| EP-0754694-A1 | Process for the preparation of secondary arylphosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-22 | — | — | EP | claimed |
| CN-102884025-A | Production of ethylenically unsaturated carboxylic acid salts by the carboxylation of alkenes | BASF SE | 2013-01-16 | — | — | CN | disclosed |
| US-5648549-A | Process for the preparation of secondary arylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| EP-0754694-A1 | Process for the preparation of secondary arylphosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-4528404-A | High temperature hydroformylation in the presence of triarylphosphine rhodium carbonyl hydride complex catalyst systems | EXXON RESEARCH AND ENGINEERING CO. (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0139702-A1 | HIGH TEMPERATURE HYDROFORMYLATION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
| WO-1984003697-A1 | HIGH TEMPERATURE HYDROFORMYLATION | EXXON RESEARCH ENGINEERING CO (US) | 1984-09-27 | — | — | WO | disclosed |