Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.54 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.54 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.54 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.54 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.54 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.54 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.54 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.54 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.54 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.54 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.54 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.54 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.54 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.54 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.54 |
| ▸ | NDUFB6 | O95139 | 1/20 | 0.54 |
| ▸ | NDUFA3 | O95167 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899481 | 1.00 | ALOX15 (0.54) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL27662550 | 0.99 | ALOX15 (0.55) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL24183240 | 0.99 | ALOX15 (0.55) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL24183231 | 0.90 | ALOX15 (0.60) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL24183242 | 0.84 | ALOX15 (0.53) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL7536951 | 0.83 | TRPV1 (0.56) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL11757158 | 0.83 | TRPV1 (0.56) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL25231921 | 0.82 | ALOX15 (0.53) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL29799204 | 0.82 | ALOX15 (0.53) | ALOX15TDP1KDM4ENDUFS8COXFA4 | |
| SCHEMBL11762159 | 0.82 | ALOX15 (0.55) | ALOX15TDP1KDM4ENDUFS8COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10201510-B2 | Compositions and methods for treatment of neurological symptoms associated with alcohol-withdrawal and for convulsive seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-02-12 | — | — | US | claimed |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-11-20 | — | — | US | claimed |
| WO-2006086372-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL SYMPTOMS ASSOCIATED WITH ALCOHOL-WITHDRAWAL AND FOR CONVULSIVE SEIZURE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2006-08-17 | — | — | WO | claimed |
| US-10201510-B2 | Compositions and methods for treatment of neurological symptoms associated with alcohol-withdrawal and for convulsive seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
| US-10201510-B2 | Compositions and methods for treatment of neurological symptoms associated with alcohol-withdrawal and for convulsive seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-11-20 | — | — | US | disclosed |
| WO-2006086372-A3 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL SYMPTOMS ASSOCIATED WITH ALCOHOL-WITHDRAWAL AND FOR CONVULSIVE SEIZURE | UNIV OREGON HEALTH & SCIENCE (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2006086372-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL SYMPTOMS ASSOCIATED WITH ALCOHOL-WITHDRAWAL AND FOR CONVULSIVE SEIZURE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006086372-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL SYMPTOMS ASSOCIATED WITH ALCOHOL-WITHDRAWAL AND FOR CONVULSIVE SEIZURE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201510-B2 | Compositions and methods for treatment of neurological symptoms associated with alcohol-withdrawal and for convulsive seizure | ADH1C, ADH1A, CHRNA10 | ALOX15 632/4885TDP1 1254/4885KDM4E 2450/4885 |
| US-20080286209-A1 | Compositions and Methods for Treatment of Neurological Symptoms Associated with Alcohol-Withdrawal and for Consulsive Seizure | PNMT, ADH1A, CHRNA10 | ALOX15 1764/4885TDP1 1136/4885KDM4E 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.