Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906291 | 0.72 | SIGMAR1 (0.35) | — | |
| SCHEMBL4899561 | 0.70 | — | — | |
| SCHEMBL10758039 | 0.66 | GABRA1 (0.44) | GABRA1GABRB2 | |
| SCHEMBL7594295 | 0.64 | CA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL9511180 | 0.63 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL29501701 | 0.62 | SIGMAR1 (0.43) | — | |
| SCHEMBL1349024 | 0.61 | HSPA5 (0.52) | — | |
| SCHEMBL1079614 | 0.61 | PTGER4 (0.40) | GABRA1GABRB2 | |
| SCHEMBL2542978 | 0.60 | TRPA1 (0.43) | GABRA1GABRB2 | |
| SCHEMBL8165914 | 0.60 | HSPA5 (0.40) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324970-B1 | RETINOIDS FOR THE TREATMENT OF EMPHYSEMA | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | EP | disclosed |