SCHEMBL4899647

SCHEMBL4899647

C1=CC(c2cc3ccccc3[nH]2)c2cccc3cccc1c23

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.34
BRD4 O60885 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ESR1 P03372 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
FLT3 P36888 1/20 0.32
CYP2A6 P11509 1/20 0.32
DAO P14920 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
SRD5A2 P31213 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DDO Q99489 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5353485 0.88 AOC3 (0.38) AOC3BRD4NPC1RAB9ALOXL2
SCHEMBL28135570 0.75 ALDH1A1 (0.37) AOC3NPC1RAB9AKDM4EMAPT
SCHEMBL28445320 0.75 KIF11 (0.43) KDM4EMAPTHPGDHSD17B10
SCHEMBL9473556 0.74 CA12 (0.39) BRD4MAPT
SCHEMBL3470484 0.73 MEN1 (0.37) NPC1RAB9AMAPTHPGDHSD17B10
SCHEMBL29152783 0.73
SCHEMBL29152742 0.73
SCHEMBL26647477 0.72 PARP1 (0.35) BRD4
SCHEMBL21994346 0.72 KDM1A (0.40) CYP2A6KDM4EMAPTHPGDHSD17B10
SCHEMBL7849802 0.72 KDM4E (0.41) KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570363-B1 METHOD OF TESTING OILS COMMW OF AUSTRALIA (AU) 1998-06-24 EP claimed
US-20080067110-A1 Method and apparatus for improving the oxidative thermal stability of distillate fuel BP OIL INTERNATIONAL LIMITED (GB) 2008-03-20 US disclosed
US-20050103686-A1 Method and apparatus for improving the oxidative thermal stability of distillate fuel BP OIL INTERNATIONAL LIMITED (GB) 2005-05-19 US disclosed
EP-1499698-A2 METHOD AND APPARATUS FOR IMPROVING THE OXIDATIVE THERMAL STABILITY OF DISTILLATE FUEL BP OIL INTERNATIONAL LIMITED (GB) 2005-01-26 EP disclosed
WO-2003091361-A2 METHOD AND APPARATUS FOR IMPROVING THE OXIDATIVE THERMAL STABILITY OF DISTILLATE FUEL BP OIL INTERNATIONAL LIMITED (GB) 2003-11-06 WO disclosed
EP-0570363-B1 METHOD OF TESTING OILS COMMW OF AUSTRALIA (AU) 1998-06-24 EP disclosed
US-5378632-A Detection of phenalenones and phenalanones by reaction with indole compound in presence of acid catalyst, diesel oils THE COMMONWEALTH OF AUSTRALIA (AU) 1995-01-03 US disclosed
EP-0570363-A1 METHOD OF TESTING OILS THE COMMONWEALTH OF AUSTRALIA (AU) 1993-11-24 EP disclosed
EP-0570363-A4 METHOD OF TESTING OILS. COMMW OF AUSTRALIA (AU) 1992-10-12 EP disclosed
EP-0502008-A1 IMPROVING STORAGE STABILITY OF OILS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1992-09-09 EP disclosed
WO-1991007475-A1 IMPROVING STORAGE STABILITY OF OILS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1991-05-30 WO disclosed
WO-1991005242-A1 METHOD OF TESTING OILS COMMONWEALTH OF AUSTRALIA (AU) 1991-04-18 WO disclosed