SCHEMBL489976

SCHEMBL489976

N#Cc1ccccc1S(=O)(=O)Cl

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
HTT P42858 1/20 0.58
SLC22A12 Q96S37 6/20 0.49
POLB P06746 1/20 0.46
PKM P14618 1/20 0.44
LMNA P02545 1/20 0.43
HSD11B1 P28845 1/20 0.43
SLC40A1 Q9NP59 1/20 0.42
KAT6A Q92794 1/20 0.42
TSHR P16473 1/20 0.41
FBP1 P09467 1/20 0.40
TRPV4 Q9HBA0 1/20 0.40
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NR1H3 Q13133 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29948777 1.00 ALDH1A1 (0.58) ALDH1A1HTTSLC22A12POLBPKM
Hydrochloric Acid SCHEMBL3938103 0.98 ALDH1A1 (0.56) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL8666148 0.82 ALDH1A1 (0.43) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL8514629 0.82 ALDH1A1 (0.62) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL30468568 0.82 ALDH1A1 (0.62) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL7761256 0.82 ALDH1A1 (0.44) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL27709888 0.81 ALDH1A1 (0.50) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL25170432 0.80 ALDH1A1 (0.43) ALDH1A1HTTSLC22A12POLBPKM
SCHEMBL5242541 0.80 HTT (0.43) ALDH1A1HTTSLC22A12POLBSLC40A1
SCHEMBL31387937 0.80 ALDH1A1 (0.47) ALDH1A1HTTSLC22A12POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 818 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-106831814-B A kind of thieno [3,2-d] miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application 山东大学 2018-11-23 CN claimed
CN-106831814-A A kind of thieno [3,2 d] RTIs of miazines HIV 1 and its preparation method and application 山东大学 2017-06-13 CN claimed
CN-103910590-B A kind of biaryl compounds and preparation method thereof SHAOXING UNIVERSITY (CN) 2015-12-02 CN claimed
CN-103910590-A Biaryl compound and preparation method thereof UNIV SHAOXING 2014-07-09 CN claimed
EP-2385831-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT The UAB Research Foundation (US) 2011-11-16 EP claimed
US-20110254866-A1 INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE SONY CORPORATION (JP) 2011-10-20 US claimed
WO-2010123591-A2 SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT THE UAB RESEARCH FOUNDATION (US) 2010-10-28 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-0770599-B1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS (JP) 2002-08-07 EP claimed
US-5811571-A HALOGENATING AN AROMATIC OR HETEROAROMATIC METHYL SULFIDE OR METHYL SULFOXIDE IN PRESENCE OF WATER SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-09-22 US claimed
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP claimed
US-5081275-A Process for the preparation of 2-fluorobenzonitrile from saccharin ALLIED-SIGNAL INC. (US) 1992-01-14 US claimed
JP-8143530-A None JP disclosed
CN-117177975-B Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2026-05-19 CN disclosed
US-12540115-B2 Inhibitors of phospholipid synthesis and methods of use THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-02-03 US disclosed
US-4490527-A Benzo-fused heterocyclic anti-ulcer agents AMERICAN HOME PRODUCTS CORPORATION (US) 1984-12-25 US disclosed
US-4461901-A ANTIULCER AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1984-07-24 US disclosed
EP-0081955-A2 Benzo-fused heterocyclic compounds AMERICAN HOME PRODUCTS CORPORATION (US) 1983-06-22 EP disclosed
US-4136253-A ANTIBIOTICS PFIZER INC. (US) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540115-B2 Inhibitors of phospholipid synthesis and methods of use LCAT, DGAT1, DGAT2 ALDH1A1 1934/4885HTT 3807/4885SLC22A12 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.