SCHEMBL8514629

SCHEMBL8514629

N#Cc1ccccc1S(=O)(=O)c1ccccc1C#N

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
HTT P42858 1/20 0.62
POLB P06746 2/20 0.62
LMNA P02545 1/20 0.57
HSD11B1 P28845 1/20 0.53
SLC22A12 Q96S37 3/20 0.47
PKM P14618 1/20 0.46
ABCC9 O60706 1/20 0.46
ABCC8 Q09428 1/20 0.46
KCNJ11 Q14654 1/20 0.46
KCNJ8 Q15842 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
TSHR P16473 1/20 0.44
GAA P10253 1/20 0.44
KDM4E B2RXH2 2/20 0.44
SLC40A1 Q9NP59 1/20 0.44
KAT6A Q92794 1/20 0.44
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468568 1.00 ALDH1A1 (0.62) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL1146161 0.87 HSD11B1 (0.59) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL2047783 0.84 ALDH1A1 (0.60) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL4520419 0.84 ALDH1A1 (0.60) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL3263174 0.84 POLB (0.52) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL3877411 0.82 ALDH1A1 (0.58) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL8779849 0.82 ALDH1A1 (0.58) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL489976 0.82 ALDH1A1 (0.58) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL291455 0.82 CA2 (0.58) ALDH1A1HTTPOLBLMNAHSD11B1
SCHEMBL10658848 0.82 ALDH1A1 (0.58) ALDH1A1HTTPOLBLMNAHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112601662-B Laminate, metal foil-clad laminate, patterned laminate with metal foil, laminate having laminate structure, printed circuit board, multilayer coreless substrate, and method for producing same 三菱瓦斯化学株式会社 2023-07-07 CN disclosed
EP-2457651-B1 CHEMICAL REACTOR AND ITS USAGE IN CHEMICAL REACTION BEIJING SIJIANTONG TECHNOLOGY & DEV CO LTD (CN) 2015-05-20 EP disclosed
US-20120186972-A1 CHEMICAL REACTOR AND ITS USAGE IN CHEMICAL REACTION BEIJING SIJIANTONG TECHNOLOGY & DEVELOPMENT CO., LTD. (CN) 2012-07-26 US disclosed
EP-2457651-A1 CHEMICAL REACTOR AND ITS USAGE IN CHEMICAL REACTION Beijing Sijiantong Technology&Development Co., Ltd (CN) 2012-05-30 EP disclosed