Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079881 | 0.89 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL4899605 | 0.86 | OPRD1 (0.53) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL14352723 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL9912061 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL2846505 | 0.79 | GAA (0.68) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL10151018 | 0.78 | GAA (0.66) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL28686900 | 0.77 | LMNA (0.61) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL8915944 | 0.76 | LMNA (0.65) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL13187482 | 0.76 | LMNA (0.65) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL8922006 | 0.76 | GAA (0.72) | ALDH1A1LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153917-A1 | Sigma Receptor Ligands | UCB PHARMA, S.A. (BE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153917-A1 | Sigma Receptor Ligands | SIGMAR1, TMEM97, OPRL1 | ALDH1A1 2385/4885LMNA 2072/4885MEN1 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.