Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900968 | 0.91 | ALDH1A1 (0.48) | TSHRALDH1A1ADORA3MAPTSMN1; SMN2 | |
| SCHEMBL4901487 | 0.80 | MEN1 (0.36) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4899230 | 0.76 | RAB9A (0.45) | ALDH1A1ADORA3MAPTSMN1; SMN2CSNK1D | |
| SCHEMBL4904524 | 0.71 | RAB9A (0.48) | ADORA3MAPTSMN1; SMN2CSNK1DNPC1 | |
| SCHEMBL8861145 | 0.71 | KMT2A (0.45) | TSHRALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4903034 | 0.71 | NOS2 (0.36) | TSHRALDH1A1KMT2A | |
| SCHEMBL21248208 | 0.66 | SMN1; SMN2 (0.42) | ALDH1A1MAPTSMN1; SMN2CSNK1DL3MBTL1 | |
| SCHEMBL20660562 | 0.65 | SMN1; SMN2 (0.46) | TSHRALDH1A1MAPTSMN1; SMN2CSNK1D | |
| SCHEMBL6228468 | 0.65 | TSHR (0.45) | TSHRALDH1A1MAPTSMN1; SMN2CSNK1D | |
| SCHEMBL15550285 | 0.65 | KMT2A (0.47) | TSHRALDH1A1ADORA3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | PFIZER INC. (US) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | SPR, TPMT, IMPDH1 | TSHR 3874/4885ALDH1A1 84/4885ADORA3 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.