Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | HPGD | P15428 | 8/20 | 0.77 |
| ▸ | GLA | P06280 | 6/20 | 0.77 |
| ▸ | GAA | P10253 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753357 | 0.87 | MAPT (0.81) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL4752756 | 0.79 | MAPT (0.84) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL4753163 | 0.69 | HSD17B10 (0.74) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL29748988 | 0.67 | USP2 (0.76) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4954775 | 0.67 | HPGD (0.53) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL20159109 | 0.66 | MTOR (0.50) | TP53HTTMAPK1 | |
| SCHEMBL17156578 | 0.64 | KDM4E (0.47) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL2038550 | 0.63 | NPSR1 (0.54) | HSD17B10KDM4EALDH1A1HPGDGLA | |
| SCHEMBL23244275 | 0.63 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2036243 | 0.63 | HTT (0.50) | HSD17B10KDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |