Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 18/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 18/20 | 0.52 |
| ▸ | RELA | Q04206 | 18/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633738 | 0.80 | NFKB1 (0.56) | NFKB1NFKB2RELA | |
| SCHEMBL10733681 | 0.76 | NFKB1 (0.52) | NFKB1NFKB2RELA | |
| SCHEMBL8045126 | 0.76 | NFKB1 (0.62) | NFKB1NFKB2RELA | |
| SCHEMBL6749348 | 0.76 | NFKB1 (0.62) | NFKB1NFKB2RELA | |
| SCHEMBL8048594 | 0.75 | NFKB1 (0.72) | NFKB1NFKB2RELA | |
| SCHEMBL8044013 | 0.75 | NFKB1 (0.68) | NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL8970554 | 0.75 | NFKB1 (0.61) | NFKB1NFKB2RELA | |
| SCHEMBL24102069 | 0.74 | DPP4 (0.45) | NFKB1NFKB2RELA | |
| SCHEMBL8970368 | 0.73 | NFKB1 (0.52) | NFKB1NFKB2RELA | |
| SCHEMBL10510563 | 0.68 | NFKB1 (0.59) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | C1S, CHRM1, C1R | NFKB1 4261/4885NFKB2 3176/4885RELA 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.