Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 18/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 18/20 | 0.56 |
| ▸ | RELA | Q04206 | 18/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902548 | 0.80 | NFKB1 (0.52) | NFKB1NFKB2RELA | |
| SCHEMBL6749348 | 0.80 | NFKB1 (0.62) | NFKB1NFKB2RELA | |
| SCHEMBL8044013 | 0.78 | NFKB1 (0.68) | NFKB1NFKB2RELA | |
| SCHEMBL8048594 | 0.78 | NFKB1 (0.72) | NFKB1NFKB2RELA | |
| SCHEMBL8045126 | 0.76 | NFKB1 (0.62) | NFKB1NFKB2RELA | |
| SCHEMBL10733681 | 0.76 | NFKB1 (0.52) | NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL8970554 | 0.75 | NFKB1 (0.61) | NFKB1NFKB2RELA | |
| SCHEMBL8970368 | 0.73 | NFKB1 (0.52) | NFKB1NFKB2RELA | |
| SCHEMBL10510563 | 0.71 | NFKB1 (0.59) | NFKB1NFKB2RELA | |
| SCHEMBL24102069 | 0.71 | DPP4 (0.45) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090542-B2 | Methods for labeling a substrate using a hetero-diels-alder reaction | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| EP-2419095-A2 | PHARMACEUTICALLY ACTIVE COMPOSITIONS COMPRISING OXIDATIVE STRESS MODULATORS (OSM), NEW CHEMICAL ENTITIES, COMPOSITIONS AND USES | Colby Pharmaceutical Company (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20110257047-A1 | Methods for Labeling a Substrate Using a Hetero-Diels-Alder Reaction | NATIONAL SCIENCE FOUNDATION | 2011-10-20 | — | — | US | disclosed |
| US-20100297262-A1 | PHARMACEUTICALLY ACTIVE COMPOSITIONS COMPRISING OXIDATIVE STRESS MODULATORS (OSM), NEW CHEMICAL ENTITIES, COMPOSITIONS AND USES | COLBY PHARMACEUTICAL COMPANY (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2010121177-A2 | PHARMACEUTICALLY ACTIVE COMPOSITIONS COMPRISING OXIDATIVE STRESS MODULATORS (OSM), NEW CHEMICAL ENTITIES, COMPOSITIONS AND USES | COLBY PHARMACEUTICAL COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297262-A1 | PHARMACEUTICALLY ACTIVE COMPOSITIONS COMPRISING OXIDATIVE STRESS MODULATORS (OSM), NEW CHEMICAL ENTITIES, COMPOSITIONS AND USES | MPO, HMOX1, LPO | NFKB1 194/4885NFKB2 189/4885RELA 113/4885 |
| US-20110257047-A1 | Methods for Labeling a Substrate Using a Hetero-Diels-Alder Reaction | SQOR, NQO1, MSMO1 | NFKB1 2671/4885NFKB2 1487/4885RELA 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.