Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765174 | 0.79 | — | — | |
| SCHEMBL20844632 | 0.78 | PNMT (0.60) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL18769305 | 0.78 | TAAR1 (0.46) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL13977269 | 0.78 | TAAR1 (0.46) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL283558 | 0.77 | TAAR1 (0.39) | TAAR1IDO1 | |
| SCHEMBL11763142 | 0.76 | TAAR1 (0.50) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL15345566 | 0.76 | TAAR1 (0.45) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL3853373 | 0.76 | TAAR1 (0.45) | TAAR1PNMTIDO1DPP4LOXL2 | |
| SCHEMBL13019656 | 0.75 | GABRA1 (0.48) | TAAR1IDO1 | |
| SCHEMBL11741449 | 0.75 | APOBEC3G (0.39) | TAAR1IDO1ASH1LKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| US-8557853-B2 | Aryl fluoroethyl ureas acting as alpha 2 adrenergic agents | ALLERGAN, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ALLERGHAN, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ADRB2, ADRA2C, ADRA2A | TAAR1 27/4885PNMT 73/4885IDO1 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.