Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 14/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907398 | 0.90 | ALDH1A1 (0.42) | STAT3CAMK2ATSHR | |
| SCHEMBL4899843 | 0.81 | LMNA (0.44) | KDM4EPOLB | |
| SCHEMBL4906110 | 0.80 | POLB (0.43) | GAAKDM4ETSHRPOLB | |
| SCHEMBL4899746 | 0.78 | LMNA (0.42) | GAAKDM4ETSHRPOLB | |
| SCHEMBL4895518 | 0.78 | MMP9 (0.48) | — | |
| SCHEMBL4903039 | 0.75 | LMNA (0.52) | STAT3POLBKDM1A | |
| SCHEMBL4906721 | 0.72 | ALDH1A1 (0.46) | GAAKDM4ETSHRPOLB | |
| SCHEMBL4905213 | 0.72 | ALDH1A1 (0.40) | KDM4EPOLB | |
| SCHEMBL4898318 | 0.71 | POLB (0.37) | GAAKDM4ETSHRPOLB | |
| SCHEMBL4902618 | 0.70 | ALDH1A1 (0.46) | KDM4ETSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | STAT3 1856/4885GAA 1367/4885CAMK2A 2101/4885 |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PPARA, PPARG, PPARD | STAT3 1856/4885GAA 1367/4885CAMK2A 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.