SCHEMBL4903237

SCHEMBL4903237

CCCS(=O)(=O)ON=C(c1ccc(OC)cc1)C(F)(F)S(=O)(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.43
PTGS2 P35354 2/20 0.41
HTT P42858 1/20 0.39
GAA P10253 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.38
MMP9 P14780 2/20 0.37
MMP13 P45452 2/20 0.37
MMP1 P03956 2/20 0.37
KMT2A Q03164 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
MEN1 O00255 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903190 0.92 HSD11B1 (0.45) HSD11B1PTGS2HTTGAATAS2R14
SCHEMBL4895537 0.91 TDP1 (0.35) HSD11B1PTGS2HTTGAAKMT2A
SCHEMBL4905883 0.86 RECQL (0.40) PTGS2GAAKMT2ATDP1MEN1
SCHEMBL4903202 0.86 HSD11B1 (0.45) HSD11B1PTGS2HTTGAATAS2R14
SCHEMBL4903678 0.85 HSD11B1 (0.44) HSD11B1PTGS2HTTGAATAS2R14
SCHEMBL12293161 0.85 RECQL (0.39) PTGS2GAAKMT2ATDP1MEN1
SCHEMBL7246388 0.85 RECQL (0.39) PTGS2GAAKMT2ATDP1MEN1
SCHEMBL6873824 0.84 PTGS2 (0.36) PTGS2MMP9MMP13MMP1KMT2A
SCHEMBL4900867 0.83 RECQL (0.39) HSD11B1PTGS2GAAKMT2ATDP1
SCHEMBL6875352 0.83 PTGS2 (0.37) PTGS2MMP9MMP13MMP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed