Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870741 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL9215081 | 0.71 | MEN1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL112247 | 0.71 | MEN1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7319715 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL142091 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL14269005 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL1408362 | 0.71 | SIGMAR1 (0.55) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL1268068 | 0.71 | MEN1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL142090 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL982352 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080104774-A1 | AMMONIA-FREE OXIDATION DYE FOR DYEING KERATIN FIBERS WITH ATMOSPHERIC OSYGEN SERVING AS THE SOLE OXIDIZING AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080104774-A1 | AMMONIA-FREE OXIDATION DYE FOR DYEING KERATIN FIBERS WITH ATMOSPHERIC OSYGEN SERVING AS THE SOLE OXIDIZING AGENT | KRT18, AKR1C4, OAT | ALDH1A1 475/4885MEN1 2848/4885KMT2A 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.