Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625280 | 1.00 | MEN1 (0.54) | MEN1KMT2AALDH1A1USP2CDK4 | |
| Hydrochloric Acid SCHEMBL1163794 | 0.98 | MEN1 (0.52) | MEN1KMT2AALDH1A1USP2CDK4 | |
| Propane SCHEMBL6216652 | 0.92 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL483231 | 0.86 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL29612036 | 0.86 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL5739994 | 0.86 | DRD2 (0.53) | MEN1KMT2AALDH1A1USP2CDK4 | |
| Hydrochloric Acid SCHEMBL5428326 | 0.85 | SMN1; SMN2 (0.52) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL1447375 | 0.85 | TSHR (0.48) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL1448243 | 0.83 | AVPR2 (0.46) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL9837085 | 0.83 | AVPR2 (0.46) | MEN1KMT2AALDH1A1USP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773252-B | Chiral amino indoline derivative and preparation method and application thereof | 华中师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-115209869-A | Transparent colored cosmetic composition capable of automatically changing color under ultraviolet irradiation | 因特科股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-114773252-A | Chiral amino indoline derivative and preparation method and application thereof | 华中师范大学 | 2022-07-22 | — | — | CN | claimed |
| CN-108033906-B | Preparation method of silodosin intermediate | 常州瑞明药业有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-102971290-A | Cationic 6-aminoindolines, dyeing compositions containing them, processes and uses thereof | OREAL | 2013-03-13 | — | — | CN | claimed |
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |
| US-8258130-B2 | Pyrimidine hydrazide compounds as PGDS inhibitors | SANOFI (FR) | 2012-09-04 | — | — | US | claimed |
| US-20100048568-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2010-02-25 | — | — | US | claimed |
| EP-2142516-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | Sanofi-Aventis (FR) | 2010-01-13 | — | — | EP | claimed |
| CN-100475818-C | Indolinospiropyran compounds and methods for manufacture | ESSILOR INT (FR) | 2009-04-08 | — | — | CN | claimed |
| WO-2002036113-A1 | COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) | RESPIRATORIUS AB (SE) | 2002-05-10 | — | — | WO | claimed |
| WO-2002036114-A1 | COMPOSITION COMPRISING SEROTONIN RECEPTOR ANTAGONISTS, 5 HT-2 AND 5 HT-3 | RESPIRATORIUS AB (SE) | 2002-05-10 | — | — | WO | claimed |
| WO-2001095902-A9 | A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS | — | 2002-04-25 | — | — | WO | claimed |
| WO-2001095902-A1 | A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS | RESPIRATORIUS AB (SE) | 2001-12-20 | — | — | WO | claimed |
| WO-2001095903-A1 | 5-HT3 RECEPTOR ANTAGONISTS FOR TREATMENT OF DISORDERS INVOLVING AIRWAY CONSTRICTION | RESPIRATORIUS AB (SE) | 2001-12-20 | — | — | WO | claimed |
| CN-1259039-A | Keratin fibre oxidation dyeing composition and dyeing method using same | OREAL (FR) | 2000-07-05 | — | — | CN | claimed |
| CN-1254552-A | Ceratin-fibre composition for oxidation dying and method for dying with solid composition | OREAL (FR) | 2000-05-31 | — | — | CN | claimed |
| CN-1253547-A | 1,4-substituted cyclic amine derivatives | EISAI CO LTD (JP) | 2000-05-17 | — | — | CN | claimed |
| EP-0497697-B1 | Keratinous fibres dyeing process with isatine associated with an aminoindol or an aminoindoline, and composition therefor | OREAL (FR) | 1995-12-06 | — | — | EP | claimed |
| EP-0497697-A1 | Keratinous fibres dyeing process with isatine associated with an aminoindol or an aminoindoline, and composition therefor | L'OREAL (FR) | 1992-08-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048568-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | HRH2, HRH1, HRH4 | MEN1 4322/4885KMT2A 3378/4885ALDH1A1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.