Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391646 | 0.79 | ALDH1A1 (0.40) | PTPN2PTPN1 | |
| SCHEMBL29370031 | 0.75 | GAA (0.51) | — | |
| SCHEMBL16351494 | 0.74 | ABL1 (0.33) | — | |
| SCHEMBL289208 | 0.73 | ATM (0.40) | PTPN2PTPN1 | |
| SCHEMBL28612089 | 0.71 | ATM (0.39) | — | |
| SCHEMBL18806836 | 0.61 | ABL1 (0.34) | — | |
| SCHEMBL1880902 | 0.59 | IDO1 (0.41) | — | |
| SCHEMBL29726936 | 0.59 | IDO1 (0.41) | — | |
| SCHEMBL31460397 | 0.57 | ALDH1A1 (0.33) | — | |
| SCHEMBL29859792 | 0.57 | GAA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314243-B2 | by cyanating the aryl halides with potassium hexacyanoferrate(I) or (III) and using as catalysts, a palladium compound and a phosphine or biphosphine ligand; efficient reaction of less expensive aryl chloride on industrial scale; active catalyst; butylbis(adamantyl)phosphine or tri(t-butyl)phosphine | SALTIGO GMBH (DE) | 2012-11-20 | — | — | US | disclosed |
| US-20080194829-A1 | by cyanating the aryl halides with potassium hexacyanoferrate(I) or (III) and using as catalysts, a palladium compound and a phosphine or biphosphine ligand; efficient reaction of less expensive aryl chloride on industrial scale; active catalyst; butylbis(adamantyl)phosphine or tri(t-butyl)phosphine | SALTIGO GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| EP-1930316-A1 | Method for catalytic manufacture of aromatic or heteroaromatic nitriles | Saltigo GmbH (DE) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194829-A1 | by cyanating the aryl halides with potassium hexacyanoferrate(I) or (III) and using as catalysts, a palladium compound and a phosphine or biphosphine ligand; efficient reaction of less expensive aryl chloride on industrial scale; active catalyst; butylbis(adamantyl)phosphine or tri(t-butyl)phosphine | TST, CBR3, ALK | PTPN2 84/4885PTPN1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.