SCHEMBL4904029

SCHEMBL4904029

C=Cc1ccc(C(O)CCN2CCOCC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
HTR1A P08908 8/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894490 0.85 HRH3 (0.51) HTR1A
SCHEMBL13343050 0.81 HTR1A (0.62) HTR1A
SCHEMBL13342873 0.81 HTR1A (0.62) HTR1A
SCHEMBL1520775 0.81 HTR1A (0.62) HTR1A
SCHEMBL3358096 0.75 SIGMAR1 (0.55) HTR1A
SCHEMBL12123949 0.74 HTR1A (0.66) HTR1A
SCHEMBL11383306 0.73 POLB (0.48) KDM4E
SCHEMBL4905238 0.72 ALDH1A1 (0.68)
SCHEMBL19632873 0.72 NPC1 (0.61) KDM4E
SCHEMBL1333034 0.71 HRH3 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0282623-B1 SYNTHETIC POLYMERS WITH GLYCOSIDE SIDE CHAINS National Starch and Chemical Investment Holding Corporation (US) 1990-09-26 EP disclosed
EP-0282623-A1 Synthetic polymers with glycoside side chains National Starch and Chemical Investment Holding Corporation (US) 1988-09-21 EP disclosed
US-4673707-A REACTING SYNTHETIC POLYMERS WITH HALOHYDRIN GLYCOSIDE OF SACCHARIDES NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1987-06-16 US disclosed