Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587944 | 0.69 | SMN1; SMN2 (0.54) | NQO2KDM4EKMT2AMAPT | |
| SCHEMBL5967722 | 0.66 | MCL1 (0.49) | KDM4EHDAC8KMT2ATSHRMAPT | |
| SCHEMBL30343692 | 0.66 | MCL1 (0.49) | KDM4EHDAC8KMT2ATSHRMAPT | |
| Acetone SCHEMBL29117475 | 0.66 | KDM4E (0.55) | NTRK1DHODHPDE10APDE3BPDE3A | |
| SCHEMBL4064101 | 0.66 | PDE3B (0.48) | NQO2PDE3BPDE3AKDM4EKMT2A | |
| SCHEMBL20980503 | 0.66 | MAPT (0.42) | NQO2NTRK1PDE3BPDE3ABCHE | |
| SCHEMBL4293106 | 0.65 | PDE3B (0.47) | PDE3BPDE3AKDM4EKMT2ATSHR | |
| SCHEMBL5532401 | 0.64 | DHODH (0.49) | DHODHPDE10ASLC22A12KMT2ATSHR | |
| SCHEMBL27504693 | 0.63 | ALDH1A1 (0.54) | SLC22A12KDM4EKMT2ATSHRMAPT | |
| SCHEMBL31668450 | 0.63 | ALDH1A1 (0.54) | SLC22A12KDM4EKMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027092-A1 | 1-Acetic Acid-Indole, -Indazole and -Benzimidazole Derivatives Useful for the Treatment of Respiratory Disorders | ASTRAZENECA AB (SE) | 2008-01-31 | — | — | US | disclosed |
| CN-1906189-A | 1-acetic acid-indole, -indazole and-benzimidazole derivatives for the treatment of respiratory diseases | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027092-A1 | 1-Acetic Acid-Indole, -Indazole and -Benzimidazole Derivatives Useful for the Treatment of Respiratory Disorders | IDO1, ABAT, ECI1 | NQO2 164/4885NTRK1 3527/4885DHODH 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.