Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581334 | 0.83 | L3MBTL1 (0.70) | HDAC1HDAC7HDAC8HDAC6ABCC9 | |
| SCHEMBL4909021 | 0.80 | KMT2A (0.52) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL20941784 | 0.80 | HDAC1 (0.66) | HDAC1HDAC7HDAC8HDAC6ABCC9 | |
| SCHEMBL13656123 | 0.77 | ABCC9 (0.52) | HDAC1HDAC7HDAC8HDAC6ABCC9 | |
| SCHEMBL7523309 | 0.76 | PDK1 (0.70) | HDAC1HDAC7HDAC8HDAC6ABCC9 | |
| SCHEMBL12309897 | 0.76 | PGR (0.56) | ABCC9KCNJ11MAPTLMNATSHR | |
| SCHEMBL20941785 | 0.76 | HDAC1 (0.65) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL5785443 | 0.76 | HDAC1 (0.69) | HDAC1HDAC7HDAC8HDAC6MAPT | |
| SCHEMBL20941550 | 0.76 | MAPT (0.54) | ABCC9KCNJ11MAPTLMNATSHR | |
| SCHEMBL959690 | 0.75 | EGLN2 (0.55) | HDAC1HDAC7HDAC8HDAC6ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | claimed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | claimed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | claimed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | NQO2, CBR3, COX4I1 | HDAC1 448/4885HDAC7 1280/4885HDAC8 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.