Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 3/20 | 0.35 |
| ▸ | BRAF | P15056 | 11/20 | 0.34 |
| ▸ | RAF1 | P04049 | 9/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782957 | 0.87 | BRAF (0.42) | FASNBRAFHPGDKMT2A | |
| SCHEMBL4783689 | 0.80 | ACKR3 (0.39) | DHODHFASNBRAFRAF1HPGD | |
| SCHEMBL4781558 | 0.80 | GLS (0.41) | FASNBRAFHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4782195 | 0.76 | GPR119 (0.42) | FASNBRAFRAF1 | |
| SCHEMBL4781871 | 0.75 | MAPK14 (0.37) | BRAFMAPK14 | |
| SCHEMBL4783684 | 0.75 | ACKR3 (0.40) | FASNBRAFHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4783254 | 0.75 | MAPK14 (0.35) | MAPK14 | |
| SCHEMBL4781600 | 0.75 | TEK (0.38) | BRAFRAF1 | |
| SCHEMBL4780823 | 0.74 | ACKR3 (0.39) | DHODHBRAFHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4799754 | 0.74 | MAPK14 (0.37) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |