Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905049 | 0.96 | ABCB1 (0.45) | ABCC1ABCG2ABCB1KDM4ENPSR1 | |
| SCHEMBL4908538 | 0.83 | HPGD (0.36) | KDM4EALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL4913227 | 0.80 | MAPT (0.40) | ABCC1ABCG2NPSR1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4899154 | 0.79 | MAPT (0.39) | ABCC1ABCG2NPSR1ALDH1A1GAA | |
| SCHEMBL4910047 | 0.76 | ALDH1A1 (0.46) | ABCC1ABCG2ABCB1KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL4884319 | 0.75 | ALDH1A1 (0.45) | ABCC1ABCG2ABCB1KDM4ENPSR1 | |
| SCHEMBL4907107 | 0.75 | MAPT (0.48) | ABCC1ABCG2ABCB1KDM4ENPSR1 | |
| SCHEMBL4901771 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1POLBLMNATSHR | |
| SCHEMBL4901811 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1GAALMNATSHR | |
| Hydrochloric Acid SCHEMBL4926745 | 0.71 | NPC1 (0.48) | KDM4EALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | ABCC1 64/4885ABCG2 101/4885ABCB1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.