Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901811 | 0.84 | KDM4E (0.38) | MAPTRAB9AALDH1A1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL4911304 | 0.83 | KDM4E (0.41) | MAPTRAB9AALDH1A1CYP3A4KMT2A | |
| SCHEMBL4913227 | 0.83 | MAPT (0.40) | MAPTRAB9AABCC1ABCG2ALDH1A1 | |
| SCHEMBL4908143 | 0.83 | HTR3E (0.48) | MAPTRAB9AALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4899154 | 0.82 | MAPT (0.39) | MAPTRAB9AABCC1ABCG2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4901792 | 0.82 | HTR3E (0.47) | MAPTRAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL4922170 | 0.82 | NPC1 (0.49) | RAB9AALDH1A1HSD17B10SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL4926745 | 0.81 | NPC1 (0.48) | RAB9AALDH1A1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL4910047 | 0.79 | ALDH1A1 (0.46) | MAPTRAB9AABCB1ABCC1ABCG2 | |
| SCHEMBL4908538 | 0.78 | HPGD (0.36) | RAB9AALDH1A1HSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | claimed |
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | TYMP, HPRT1, IMPDH1 | MAPT 4400/4885RAB9A 3384/4885PLD1 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.