Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4917919 | 0.86 | RORC (0.58) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL29492442 | 0.80 | TSHR (0.61) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL1104213 | 0.80 | TSHR (0.61) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL21756935 | 0.79 | LMNA (0.59) | TSHRALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL29663703 | 0.78 | GAA (0.59) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL14154101 | 0.78 | GAA (0.59) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL93071 | 0.78 | GAA (0.59) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL3399797 | 0.78 | GAA (0.59) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL30893081 | 0.78 | LMNA (0.64) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL4401739 | 0.78 | LMNA (0.64) | TSHRRORCUSP2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | BAKER MAX T | 2008-12-18 | — | — | US | disclosed |
| US-7312250-B2 | Fluorine-substituted alkyl phenol compounds and their uses | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2003077894-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | IOWA RESEARCH FOUNDATION, UNIVERSITY OF | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | AFF4, AFF1, AFF2 | TSHR 1138/4885RORC 278/4885USP2 3464/4885 |
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | AFF4, AFF1, AFF2 | TSHR 1138/4885RORC 278/4885USP2 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.