SCHEMBL490612

SCHEMBL490612

C=CC(=O)N[C@@H](CCC(N)=O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
KMT2A Q03164 2/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA2 P00918 4/20 0.33
CA1 P00915 3/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
BMP1 P13497 1/20 0.33
NOD1 Q9Y239 1/20 0.32
CYP2C19 P33261 1/20 0.32
HPGDS O60760 1/20 0.31
MMP2 P08253 2/20 0.31
MMP9 P14780 2/20 0.31
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490611 1.00 TSHR (0.41) TSHRKMT2AALOX15BLMPMP22
SCHEMBL8185221 0.87 KMT2A (0.47) TSHRKMT2AALOX15BLMPMP22
SCHEMBL23390991 0.87 FOLH1 (0.44) TSHRKMT2ABLMCA1CYP2C19
SCHEMBL8185224 0.87 KMT2A (0.47) TSHRKMT2AALOX15BLMPMP22
SCHEMBL490075 0.81 TSHR (0.43) TSHRKMT2AALDH1A1MAPK1TDP1
SCHEMBL490074 0.81 TSHR (0.43) TSHRKMT2AALDH1A1MAPK1TDP1
SCHEMBL8374067 0.79 HPGDS (0.42) TSHRALDH1A1MAPK1TDP1CA1
SCHEMBL8374065 0.79 HPGDS (0.42) TSHRALDH1A1MAPK1TDP1CA1
SCHEMBL8376938 0.79 TSHR (0.45) TSHRALDH1A1MAPK1TDP1CA2
SCHEMBL8376937 0.79 TSHR (0.45) TSHRALDH1A1MAPK1TDP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084285-A1 THERMO-SWITCHABLE PRESSURE-SENSITIVE ADHESIVES NORTHEASTERN UNIVERSITY 2025-03-13 US claimed
EP-3640305-B1 USE OF A POLYMER WITH UCST IN A COATING COMPOSITION, IN PARTICULAR FOR PAINT, TO IMPROVE DRYING CROMOLOGY (FR) 2024-12-04 EP claimed
US-20230285893-A1 WATER SORBING MATERIALS AND RELATED SYSTEMS AND METHODS UNIV KHALIFA SCIENCE & TECHNOLOGY (AE) 2023-09-14 US claimed
EP-3640305-A1 USE OF A POLYMER WITH UCST IN A COATING COMPOSITION, IN PARTICULAR FOR PAINT, TO IMPROVE DRYING Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2020-04-22 EP claimed
US-20160280572-A1 POLYMERS FOR FLOCCULATION, DEWATERING AND CONSOLIDATION OF OIL SANDS FLUID FINE TAILINGS, MINE TAILINGS AND SOLID PARTICULATE SUSPENSIONS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2016-09-29 US claimed
US-12440804-B2 Water sorbing materials and related systems and methods Khalifa University of Science and Technology (AE) 2025-10-14 US disclosed
US-20250084285-A1 THERMO-SWITCHABLE PRESSURE-SENSITIVE ADHESIVES NORTHEASTERN UNIVERSITY 2025-03-13 US disclosed
EP-3640305-B1 USE OF A POLYMER WITH UCST IN A COATING COMPOSITION, IN PARTICULAR FOR PAINT, TO IMPROVE DRYING CROMOLOGY (FR) 2024-12-04 EP disclosed
US-20230285893-A1 WATER SORBING MATERIALS AND RELATED SYSTEMS AND METHODS UNIV KHALIFA SCIENCE & TECHNOLOGY (AE) 2023-09-14 US disclosed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US disclosed
WO-2022102453-A1 TIRE 住友ゴム工業株式会社 2022-05-19 WO disclosed
WO-2022102459-A1 ELASTOMER COMPOSITION AND TIRE 住友ゴム工業株式会社 2022-05-19 WO disclosed
EP-2037272-A1 KIT FOR DETECTION/QUANTIFICATION OF ANALYTE, AND METHOD FOR DETECTION/QUANTIFICATION OF ANALYTE CHISSO CORPORATION (JP) 2009-03-18 EP disclosed
US-20090001321-A1 AQUEOUS SOLUTION OF POLYMER HAVING UPPER CRITICAL SOLUTION TEMPERATURE, AQUEOUS DISPERSION OF PARTICLE MODIFIED WITH THE POLYMER AND METHOD OF STORING THE SAME CHISSO CORPORATION (JP) 2009-01-01 US disclosed
US-20090001025-A1 AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT CHISSO CORPORATION (JP) 2009-01-01 US disclosed
EP-2009044-A1 Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same Chisso Corporation (JP) 2008-12-31 EP disclosed
EP-2009442-A2 Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit Chisso Corporation (JP) 2008-12-31 EP disclosed
US-20070203313-A1 THERMORESPONSIVE POLYMER AND PRODUCTION METHOD THEREOF CHISSO CORPORATION (JP) 2007-08-30 US disclosed
US-5883211-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis ACLARA BIOSCIENCES, INC. (US) 1999-03-16 US disclosed
WO-1997040078-A1 THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS SOANE BIOSCIENCES (US) 1997-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 TSHR 4448/4885KMT2A 4003/4885ALOX15 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.