SCHEMBL490624

SCHEMBL490624

C=CC(=O)Cn1c(=O)cc[nH]c1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2899641 0.79 APEX1 (0.48)
SCHEMBL13629866 0.77 PDE4A (0.36)
SCHEMBL128380 0.75 CYP3A4 (0.45)
SCHEMBL667246 0.73 KDM4E (0.54)
SCHEMBL338056 0.72 TYMP (0.32)
SCHEMBL5860460 0.72 LMNA (0.49)
SCHEMBL24205349 0.72 TSHR (0.44)
SCHEMBL4348692 0.72 ADRA1D (0.37)
SCHEMBL28640946 0.72 JAK3 (0.35)
SCHEMBL4347789 0.71 TYMP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486722-B1 Sensing method for biopolymers and sensing device therefor NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) 2013-07-16 US claimed
US-20130164862-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR TANAKA SABURO (JP) 2013-06-27 US claimed
US-20070218567-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) 2007-09-20 US claimed
CN-115135307-B Cell delivery vehicle 株式会社ITO 2024-11-22 CN disclosed
US-20230273455-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed
EP-4182736-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-05-24 EP disclosed
CN-115135307-A Carrier for cell delivery 株式会社ITO 2022-09-30 CN disclosed
WO-2022012798-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2022-01-20 WO disclosed
US-8486722-B1 Sensing method for biopolymers and sensing device therefor NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) 2013-07-16 US disclosed
US-20130164862-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR TANAKA SABURO (JP) 2013-06-27 US disclosed
US-8372659-B2 Sensing method for biopolymers and sensing device therefor NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) 2013-02-12 US disclosed
US-8105503-B2 Method of storing thermoresponsive polymer in state of aqueous solution CHISSO CORPORATION (JP) 2012-01-31 US disclosed
US-20110233453-A1 METHOD OF STORING THERMORESPONSIVE POLYMER IN STATE OF AQUEOUS SOLUTION CHISSO CORPORATION (JP) 2011-09-29 US disclosed
US-7976728-B2 Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same JNC CORPORATION (JP) 2011-07-12 US disclosed
EP-2009044-B1 Method of storing an aqueous dispersion of particle modified with a polymer having upper critical solution temperature JNC CORP (JP) 2011-06-15 EP disclosed
US-20090001321-A1 AQUEOUS SOLUTION OF POLYMER HAVING UPPER CRITICAL SOLUTION TEMPERATURE, AQUEOUS DISPERSION OF PARTICLE MODIFIED WITH THE POLYMER AND METHOD OF STORING THE SAME CHISSO CORPORATION (JP) 2009-01-01 US disclosed
US-20090001025-A1 AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT CHISSO CORPORATION (JP) 2009-01-01 US disclosed
EP-2009044-A1 Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same Chisso Corporation (JP) 2008-12-31 EP disclosed
EP-2009442-A2 Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit Chisso Corporation (JP) 2008-12-31 EP disclosed
US-20070218567-A1 SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) 2007-09-20 US disclosed